A case of endometrial tuberculosis leading to infertility in a young woman
Abstract
The morbidity and mortality due to tuberculosis (TB) is high worldwide, and the burden of disease among women is significant, especially in developing countries. Mycobacterium tuberculosis bacilli reach the genital tract primarily by haematogenous spread and dissemination from foci outside the genitalia with lungs as the common primary focus. Genital TB in females is a chronic disease with low-grade symptoms. The fallopian tubes are affected in almost all cases of genital TB, and along with endometrial involvement, it causes infertility in patients. A case report is presented herewith where a woman suffering from endometrial tuberculosis resulted in blockage of the fallopian tube and eventually in damaged uterus. A result of which she could not conceive even after three transfers of in vitro Fertilization.
References
2. Tripathy SN, Tripathy SN. Gynaecological tuberculosis – an update. Indian J Tuberc. 1998; 45:193–7.
3. Bhanothu V, Theophilus JP, Rozati R. Use of endo-ovarian tissue biopsy and pelvic aspirated fluid for the diagnosis of female genital tuberculosis by conventional versus molecular methods. PLoS One. 2014; 9:e98005.
4. Kulshrestha V, Kriplani A, Agarwal N, Singh UB, Rana T. Genital tuberculosis among infertile women and fertility outcome after antitubercular therapy. Int J Gynaecol Obstet. 2011; 113:229-34.
5. Charles Mariara1, Angela Koech, Peter Waweru and Alfred Murage. Endometrial tuberculosis compounding polycystic ovary syndrome in a subfertile woman: A case report. Journal of Medical Case Reports. 2016; 10:168.
6. WHO. WHO global tuberculosis report 2016. [Internet]. 2016; WHO [cited 2019 Aug 05]. Available from:
http://www.who.int/tb/publications/global_report/en/
7. Aliyu MH, Aliyu SH, Salihu HM. Female genital tuberculosis: A global review. Int J Fertil Womens Med. 2004; 49:123-36. [PubMed]
8. Namavar Jahromi B, Parsanezhad ME, Ghane-Shirazi R. Female genital tuberculosis and infertility. Int J Gynaecol Obstet. 2001; 75:269-72. [PubMed]
9. Grace GA, Devaleenal DB, and Natrajan M. Genital tuberculosis in females. Indian J Med Res. 2017 Apr; 145(4): 425-36.
10. Siladitya Bhattacharya, Neil Johnson, Hammed Akanji Tijani, Roger James Hart, Shilpi Pandey, and Ahmed Fathy Gibreel. Female infertility. Clinical Evidence. 2010; 11:819.
11. Campbell IA and Bah-Sow O. Pulmonary tuberculosis: diagnosis and treatment. BMJ. 2006; 332:1194-7.
12. Zumla A, Chakaya J, Centis R, D’Ambrosio L, et al. Tuberculosis treatment and management-an update on treatment regimens, trials, new drugs, and adjunct therapies. Lancet Respir Med. 2015; 3: 220-34.
13. Grace GA, Devaleenal DB, and Natrajan M. Genital tuberculosis in females. Indian J Med Res. 2017; 145(4): 425–436.
14. Jai B. Sharma, Sona Dharmendra, Shefali Agarwal and Eshani Sharma. Genital tuberculosis and infertility. Fertility Science and Research. 2016; 3(1).
15. Jeff Wang and Mark V Sauer. In vitro fertilization (IVF): A review of 3 decades of clinical innovation and technological advancement. Therapeutics and Clinical Risk Management. 2006; 2(4): 355-64.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The International Journal of Innovative Science & Technology affairs require a formal written transfer of copyright from the author(s) for each article published. We therefore ask you to complete and return this form, retaining a copy for your records. Your cooperation is essential and appreciated. Any delay will result in a delay in publication.
I/we have read and agree with the terms and conditions stated Page 2 of this agreement and I/we hereby confirm the transfer of all copyrights in and relating to the above-named manuscript, in all forms and media, now or hereafter known, to the International Journal of Drug Regulatory affairs, effective from the date stated below. I/we acknowledge that the IJDRA is relying on this agreement in publishing the above-named manuscript. However, this agreement will be null and void if the manuscript is not published in the IJIST.
Download link for COPYRIGHT FORM